Abstract Given that hypoxia is a persistent physiological feature of many different solid tumors and a key driver for cancer malignancy, it is thought to be a major target in cancer treatment recently.Tumor-associated macrophages (TAMs) Backpacks are the most abundant immune cells in the tumor microenvironment (TME), which have a large impact on tu
Abstract DNA methylation analysis based on supervised machine learning algorithms with static reference data, allowing diagnostic tumour typing with unprecedented precision, has quickly become a new standard of care.Whereas genome-wide diagnostic methylation profiling is mostly performed on microarrays, an increasing number of institutions addition
Management of tracheal tears can prove to be challenging in the perioperative setting.This is a rare condition that can be life threatening.Here, we present Funko Pops a case of seven-year-old boy involved in a high-speed motor vehicle collision.The child sustained multiple injuries including a near fatal head injury, multiple facial fractures, and
This investigation analyzed the attitudes of Portuguese judges and Bags victim support professionals toward intimate partner homicide committed by women.By administering an online survey disseminated by the Portuguese Superior Council for the Magistracy and the Commission for Citizenship and Gender Equality, we found that both groups of professiona
The question of how self-driving cars should behave in dilemma situations has recently attracted a lot of attention in science, media and society.A growing number of publications amass insight into the factors underlying the choices we make in such situations, often using forced-choice paradigms closely linked to the trolley dilemma.The methodology